Monday, July 8, 2024

Are Clinical Trials Necessary?? *Repost*

The simple answer?  Yes.


First of all, what ARE "clinical trials" anyway? Again, simply put, is where people volunteer for tests to help researchers investigate new treatments for a wide variety of diseases or medical conditions.
They could be looking for how people respond to a new drug or maybe the side effects.
It also could be they are comparing existing drugs to new factors in a patient's life. Clinical trials cover a wide variety of situations from new drugs or vaccines, or maybe surgical or even behavioral changes.

The World Health Organization (WHO) defines a clinical trial as:

any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes’ 

Think of where we would be without clinical trials. Without the volunteers. Animals, labs and computer simulations can only go so far. Nothing compares to testing with the human body itself. Imagine diseases or conditions like, heart disease, cancer, Alzheimer's, Parkinson's, Crohn's/colitis and now Covid-19 WITHOUT those clinical trials. More people are alive today, or living better lives, not only because of those scientists and researchers working hard behind the scenes to bring new treatments forward, but also those volunteering for clinical trials.

Let's take me for example. I was on Remicade (800 mg) every 6 weeks. Recommended dosage is 5 mg/kg, meaning 5 milligrams of Remicade for every kilogram of the patient's weight. So I was at about 10 mg/kg because I had an ongoing problem with fistulating perianal disease. My body eventually developed antibodies to the medication and was taken off it after 8 years.  I was put on Humira for two years until a forced Government non-medical switch to the Humira biosimilar.

I remember back in early 2000/2001, my gastroenterologist telling me about Remicade and asking if I wanted to be part of possible clinical trials. After discussing it in length about it, I declined. My Crohn's at the time was 'manageable' and to be honest, I was scared, even though my doctor said that from what she'd heard and read, the drug looked promising. I was worried about possible side effects, but that was more than 20 years ago.

In hindsight, I wish I had taken her advice and done it. I eventually made the decision to get the Remicade infusions many years later. I was on Remicade for 8 years and it was a "godsend", for me. I regret my decision so many years ago. I could have been part of the initial study and had the benefits from it earlier.

Researchers and scientists are constantly trying to improve life for crohn's/colitis sufferers. Whether that be by improving on current treatments or coming up with new ones. Clinical trials are happening all the time. Your doctor would know of any current trials going on or coming up but also search your country's Crohn's and colitis foundations. Many will have links on their websites to pre-screening. You might get declined, but it just means you don't meet their criteria, don't let this discourage you. I've been declined numerous times for various reasons.

The more patients who are willing to participate in clinical trials, the better the research

Wednesday, May 8, 2024

Skin Conditions

I have had another article published on inflammatoryboweldisease.net about skin conditions with Crohn's. 



Come read it here:

Skin Conditions


Visit inflammatoryboweldisease.net for more articles regarding IBD


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Tuesday, April 2, 2024

My Surgical Journey

I have had another article published on inflammatoryboweldisease.net about my surgical journey with Crohn's. 



Come read it here:

My Surgical Journey


Visit inflammatoryboweldisease.net for more articles regarding IBD

Tuesday, March 12, 2024

Crohn's Flare-Friendly Foods

I have had another article published on inflammatoryboweldisease.net about Crohn's flare-friendly foods. 



Come read it here:

Flare Friendly Foods


Visit inflammatoryboweldisease.net for more articles regarding IBD

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Wednesday, February 21, 2024

First Gastroenterology Appointment??

I have had another article published on inflammatoryboweldisease.net about what to expect at your first gastroenterology appointment. 



Come read it here:

What to expect at your first gastroenterology appointment


Visit inflammatoryboweldisease.net for more articles regarding IBD

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Thursday, December 14, 2023

Wednesday, December 6, 2023

Ask Me Anything

As part of Crohn's and Colitis Awareness Week. Tonight from 630-730 pm EST on Inflammatoryboweldisease.net I will be taking part in an "Ask Me Anything" session regarding Crohn's disease.  Have a question? Come by and take part. Hopefully, I can answer your question.

Wednesday, November 22, 2023

No Really, I AM Sick!

I have had another article published on inflammatoryboweldisease.net about having to prove that I really am sick and suffering. 



Come read it here:

No Really, I AM Sick!


Visit inflammatoryboweldisease.net for more articles regarding IBD


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Wednesday, September 13, 2023

What I Do For Crohn's Pain Relief

I have had another article published on inflammatoryboweldisease.net about IBD and what I do to help alleviate IBD pain. 


Come read it here:

What I Do For Crohn's Pain Relief


Visit inflammatoryboweldisease.net for more articles regarding IBD


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